Biohacks for Better Health

Low-Dose Naltrexone: A Miracle Treatment for Long Haul Covid
Written by: Ann Louise Gittleman, PhD, CNS
Published on: 05/28/2024
Wow. Imagine my surprise when my new primary doctor suggested we rule out “Long Haul C0VlD” with a three-month trial of targeted therapies. Never in my wildest imagination did I consider this type of diagnosis while struggling to understand my persistent voice problems, hoarseness, and excess phlegm over the past three years. Thankfully, my doctor connected the dots, tracing the onset of symptoms with the time frame of C0VlD as he had had many patients with identical symptoms.
So I want to give my followers a HEADS UP:  you or someone you know could also be suffering from Long C0VlD symptoms without realizing it. Estimates place 43% or nearly half the world population as being affected by this illness, making Long C0VlD increasingly prevalent among those recovering from C0VlD-19’s acute phase and potentially debilitating, altering daily life drastically and significantly altering its course.
It doesn’t even matter whether or not you have had the C0VlD vaccine. In my case, I believe I was impacted by a massage therapist whom I later learned had three vaccinations and who was unknowingly “shedding” the SPIKE PROTEINS. Regardless of its source or how we acquire it, the end result remains the same in far too many cases: debilitating chronic symptoms and unexplained illness.
The World Health Organization (WHO) has defined Long C0VlD as any “continuation or development of new symptoms three months post-infection with SARS-CoV-2 virus with no other clear explanation.” (Source: Yale Medicine)

Symptoms associated with Long Covid include:

  • Fatigue
  • Cognitive dysfunction including “brain fog”
  • Muscle pain
  • Joint pain
  • Shortness of breath
  • Headaches
  • Sleep disturbances
  • Chest pain
  • Heart palpitations

Low-Dose Naltrexone to The Rescue

Thanks to my new doctor, I became reacquainted with an old miracle drug and it costs next to nothing. You may know of Naltrexone from its FDA approval over 30 years ago to treat addiction at doses of 50mg or more per day. Recently however, there’s been an increased interest in using much lower doses known as Low Dose Naltrexone (LDN), typically around 1 – 4.5mg per day. LDN is now being prescribed off-label to treat:

  • Neurological Issues
  • Fibromyalgia
  • Rheumatoid Arthritis
  • Hashimoto’s and other Thyroid Issues
  • Multiple Sclerosis
  • Ulcerative Colitis
  • Crohn’s Disease
  • Anxiety
  • and now… Long Covid

A Little History

Dr. Bernard Bihari, based in New York, noticed back in 1985 that patients weaning off Naltrexone experienced positive side effects for other health conditions as they tapered off. Intrigued, Dr. Bihari conducted a placebo-controlled trial of Low Dose Naltrexone among 38 AIDS patients and saw significant reduction in opportunistic infections and improved inflammation markers. Since then dozens of studies on LDN have been completed (learn more at LDN Research Trust).
  • A 2007 study on LDN and Crohn’s disease saw 67% of patients achieve remission, leading to significant improvements in quality of life.
  • A 2023 study involving LDN and fibromyalgia saw greater reductions in baseline pain for those taking LDN than for those given placebo, along with greater life satisfaction and improvement of mood.
  • In 2023, an extensive study on LDN’s impact on rheumatoid arthritis concluded that LDN is “a promising and safe therapy to be used in some rheumatic disease.”

How Does Low-Dose Naltrexone Work?

  1. LDN Increases Endorphin Levels. LDN boosts endorphin levels, leading to improved mood and reduced pain levels.
  2. DN Calms Inflammation. LDN works on microglia cells in the brain to decrease inflammation throughout the brain and body.
  3. LDN Modulates the Body’s Immune System. LDN acts on opioid receptors found on immune cells to balance out immune response by reinstating an endorphin system balance.

Anecdotal Support

A survey of over 1,000 people on 23andMe ranked LDN as the #1 product to treat fibromyalgia, related conditions like arthritis and Crohn’s disease as well. Documentaries such as Norway’s “Our Small Country” also raised awareness of its benefits resulting in significant increases in its prescriptions nationwide.

Beyond LDN: Why Liver Support Is Crucial

The liver plays an essential role in detoxifying our bodies. It processes medications, environmental pollutants, and metabolic waste products into less harmful forms for excretion from the body. After an infection with C0VlD-19 virus, our bodies produce even greater amounts of metabolic waste products and inflammatory by-products which must be efficiently removed by our liver in order to return our health back on track.

Long Haul C0VlD Can Worsen the Liver

Chronic Long C0VlD can add an additional burden on the liver’s detoxification processes, with persistent inflammation, oxidative stress, and immune reactions all playing their parts in creating an accumulation of waste products in the body that compromises liver function and exacerbates symptoms of long haul C0VlD. This overload impairs liver function, reducing its detoxification efficiency while simultaneously exacerbating the symptoms associated with Long C0VlD.

Support Your Liver with This Key Product

To support natural liver health and provide your body with an additional cleansing boost, I recommend UNI KEY Health’s Liver-Lovin Formula.
This unique blend consists of:
  • Artichoke is a well-known liver healer, loaded with antioxidants that can assist the liver’s detox pathways while increasing bile production.
  • Chlorophyll to further facilitate elimination.
  • Taurine is an amino acid detoxifier that boosts liver bile production to facilitate fat breakdown.
Adults can take two capsules of Liver-Lovin Formula daily with meals or add them to smoothies for optimal results.

Bottom Line

LDN represents an exciting prospect for treating the chronic symptoms associated with Long C0VlD. By modulating immune response, reducing inflammation, and stimulating tissue repair processes, this treatment helps to provide significant relief for Long C0VlD sufferers. For me personally, it has been a Godsend.
>>For more information about Long C0VlD, check out my podcast interview with Dr. Jacob Teitelbaum: Post C0VlD Long Haul Syndrome and Chronic Fatigue
>>And if your doctor doesn’t know about the advantages of LDN for treating Long C0VlD, please head over to the Ageless RX website for a free online visit with a medical professional to discuss your personal treatment options. You’ll want to be fully informed of its interactions with other medications you may be taking.
Resources
Smith JP, Stock H, Bingaman S, Mauger D, Rogosnitzky M, Zagon IS. Low-dose naltrexone therapy improves active Crohn’s disease. Am J Gastroenterol. 2007 Apr;102(4):820-8. doi: 10.1111/j.1572-0241.2007.01045.x. Epub 2007 Jan 11. PMID: 17222320.
Yang J, Shin KM, Do A, Bierle DM, Abu Dabrh AM, Yin Z, Bauer BA, Mohabbat AB. The Safety and Efficacy of Low-Dose Naltrexone in Patients with Fibromyalgia: A Systematic Review. J Pain Res. 2023 Mar 21;16:1017-1023. doi: 10.2147/JPR.S395457. PMID: 36974308; PMCID: PMC10039621.
de Carvalho JF, Skare T. Low-Dose Naltrexone in Rheumatological Diseases. Mediterr J Rheumatol. 2023 Mar 31;34(1):1-6. doi: 10.31138/mjr.34.1.1. PMID: 37223594; PMCID: PMC10201089.

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