Your arteries may be narrowing long before you feel the warning signs.
Peripheral artery disease (PAD) develops gradually, often going unnoticed until blood flow is severely restricted. By the time symptoms like leg cramps, numbness, or cold feet appear, arteries may already be 60% blocked—increasing the risk of heart attack by up to 500%, stroke by more than 200%, and sometimes… even amputation.
These are health issues you do NOT want to play around with.
Watch for These Warning Signs
Peripheral artery disease (PAD) often develops silently, but certain symptoms can signal restricted blood flow. If you experience any of the following, your arteries may already be significantly narrowed:
- Leg pain or weakness – especially when walking or climbing stairs
- Cold or numb feet and toes – a sign of poor circulation
- Sores or ulcers that won’t heal – particularly on the legs or feet
- Changes in skin appearance – redness, discoloration, or a smooth, shiny texture
- Hair loss on the legs – reduced blood flow can cause thinning or patchy hair
- Faint or absent foot pulses – a key indicator of circulation issues
The Inexpensive Solution for Better Circulation
If these symptoms sound familiar, don’t wait—taking action now could protect your heart and circulation. Research shows that nicotinamide riboside (NR), a unique form of vitamin B3, boosts blood flow, supports vascular health, and helps prevent serious complications.
A recent randomized, double-blind clinical trial found that participants with peripheral artery disease (PAD) who took NR daily for six months significantly improved their walking endurance compared to the placebo group. (source: Nature.com)
The best part? NR is an affordable, over-the-counter solution—no prescription needed.
>>Where to Get This Life-Saving Form of Vitamin B
Nicotinamide riboside (NR) is available on my online Fullscript catalog. I recommend both the Liposomal Nicotinamide Riboside+ by Codeage and NR Longevity by Pure Encapsulations. (Take as directed by the manufacturer.)
The Bottom Line
Peripheral artery disease is fully preventable. Give your arteries the support they need—because protecting your heart before problems arise is the ultimate biohack!
Resources:
McDermott MM, Martens CR, Domanchuk KJ, Zhang D, Peek CB, Criqui MH, Ferrucci L, Greenland P, Guralnik JM, Ho KJ, Kibbe MR, Kosmac K, Lloyd-Jones D, Peterson CA, Sufit R, Tian L, Wohlgemuth S, Zhao L, Zhu P, Leeuwenburgh C. Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial. Nat Commun. 2024 Jun 13;15(1):5046. doi: 10.1038/s41467-024-49092-5. Erratum in: Nat Commun. 2024 Aug 12;15(1):6890. doi: 10.1038/s41467-024-51289-7. PMID: 38871717; PMCID: PMC11176364.
Bevan GH, White Solaru KT. Evidence-Based Medical Management of Peripheral Artery Disease. Arterioscler Thromb Vasc Biol. 2020 Mar;40(3):541-553. doi: 10.1161/ATVBAHA.119.312142. Epub 2020 Jan 30. PMID: 31996023.